A lot of skins are variations of different characters, so hear me out... what if they had unique voicelines based on the skin you were wearing?

Here are a few examples:

Moon Knight w/Mr. Knight

"Uhhhh... back to you, Marc...?" (plays upon respawning)

Mister Fantastic w/The Maker

"I'm going to evolve this multiverse entirely. Am I so wrong for that?" (plays upon selecting the hero)

"You know I'm superior, Stark. You just never have the courage to say it." (plays upon killing enemy Iron Man)

Venom w/Lingering Imprint

"Mind if I take the body for a spin, Eddie?" (plays upon selecting the hero)